You guys fail for not being manly with picks. It's time for the season to begin!
It's time.

Titans @ Steelers (Thursday)
Steelers - I don't see any way that the Steelers embarrass themselves on opening night. This and the Titans losing Haynesworth to FA will be the difference.
Dolphins @ Falcons
Falcons - Falcons as of last year have been much better at home, and this should be no different.
Broncos @ Bengals
Bengals - Broncos are in a significant transition year, plus we don't really know if Kyle Orton will play. Chances are, the Bengals have a shot to have one good week with Ocho Cinco.
Vikings @ Browns
Vikings - I want Favrerererere to lose, but with the Browns in their transition... and Brady Quinn being an unknown quantity, I don't see the Browns winning.
Jaguars @ Colts (division)
Colts - With Peyton getting some preseason time unlike last year, I see the Colts winning the division again. I have NFI what the Jags are this year...
Lions @ Saints
Saints - Lions will extend their losing streak. 'Nuff said.
Cowboys @ Buccaneers
Cowboys - Bucs have no QB IIRC. That and a fired offensive coordinator is probably a good bet.
Eagles @ Panthers
Eagles - Eagles to upset the mediocre Panthers... ya they have no record, but they are fucked in FA because of salary cap issues and Julius Peppers.
Chiefs @ Ravens
Ravens - Cassel's not playing, and the Ravens defense will probably hold them off.
Jets @ Texans
Texans - Does anyone see a rookie QB winning their first game period? It doesn't help when it's on the road.
Redskins @ Giants (division)
Giants - I'm not buying into the Redskins yet.
49'ers @ Cardinals (division)
Cards - 49ers have no QB, and this is a home game for the Cards...
Rams @ Seahawks (division)
Seahawks - I see them backing a bounce back year... whereas the Rams are meh IMO.
Bears @ Packers (division)
Bears - I call this my upset pick, only because it seemed like a good thing to do.
Bills @ Patriots (division)
Pats - You know there's something wrong when you fire your offensive coordinator that early.
Chargers @ Raiders (division)
Chargers - Anyone can beat the lame Raiders.